rs587780273

A SNP in the ACTB gene on chromosome 7. Its most notable genotype is T;T: Miscall in Ancestry v2c data; otherwise, Baraitser-Winter syndrome-1

Gene
ACTB
Location
Chr 75,529,594 (GRCh38)
Highest magnitude
6.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBadMiscall in Ancestry v2c data; otherwise, Baraitser-Winter syndrome-1Very important · 6.0
  2. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs587780273 on the minus strand: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.64G>A (p.Ala22Thr or A22T)

Source and license

Adapted from rs587780273 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.