rs6019
A SNP in the F5 gene on chromosome 1. Its most notable genotype is C;C: common in complete genomics
- Gene
- F5
- Location
- Chr 1169,572,275 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 11%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs6019 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 81%
- European ancestry (Utah)C;C 91%
- Han Chinese (Beijing)C;C 100%
- Japanese (Tokyo)C;C 100%
- Yoruba (Nigeria)C;C 35%
Related
Conditions, medicines and genes
Other F5 SNPs
- rs6025T;T11.4x higher risk of thrombosisVery important
- rs118203905C;CHemophilia A (severity varies)Very important
- rs118203906G;GHemophilia A (severity varies)Very important
- rs118203907C;CHemophilia A (severity varies)Very important
- rs118203908A;AHemophilia A (severity varies)Very important
- rs118203909A;AHemophilia A (severity varies)Very important
- rs118203910A;AHemophilia A (severity varies)Very important
- rs118203911G;GHemophilia A (severity varies)Very important
Notes
From SNPedia
Notes
rs6019 and rs6022 maternal smoking on PTD and gestational age. Compared with non-smoking mothers carrying rs6019(C) associated with significantly increased risk of PTD (OR(95% CI): 2.1(1.2-3.6) for GC; 5.7(2.1-15.0) for CC; p-interaction = 0.02 Polymorphism in maternal LRP8 gene is associated with fetal growth.
Source and license
Adapted from rs6019 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.