rs610932

A SNP in the MS4A6A gene on chromosome 11. Its most notable genotype is T;T: A allele associated with reduced risk of Alzheimer's in Chinese Han population.

Gene
MS4A6A
Location
Chr 1160,171,834 (GRCh38)
Highest magnitude
1.5Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
42%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodA allele associated with reduced risk of Alzheimer's in Chinese Han population.Minor · 1.525% of people
  2. G;TGoodNo summary available.Minor · 1.247% of people
  3. G;GBadNo summary available.Minor · 1.128% of people

SNPedia records rs610932 on the minus strand: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 25% G;T 47% G;G 28%
  • European ancestry (Utah)T;T 26% G;T 57% G;G 17%
  • Han Chinese (Beijing)T;T 11% G;T 47% G;G 42%
  • Japanese (Tokyo)T;T 16% G;T 36% G;G 48%
  • Yoruba (Nigeria)T;T 14% G;T 57% G;G 29%
  • African ancestry (Southwest US)T;T 18% G;T 51% G;G 32%
  • Chinese (Denver)T;T 15% G;T 44% G;G 41%
  • Gujarati IndianT;T 41% G;T 47% G;G 13%
  • Luhya (Kenya)T;T 39% G;T 47% G;G 14%
  • Mexican ancestry (Los Angeles)T;T 17% G;T 38% G;G 45%
  • Maasai (Kenya)T;T 49% G;T 45% G;G 7%
  • TuscanT;T 27% G;T 48% G;G 26%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Alzheimer's disease associated, based on large 2011 study Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease.

Source and license

Adapted from rs610932 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.