rs61751310

A SNP in the ANO2 gene on chromosome 12. Its most notable genotype is A;G: von Willebrand disease

Gene
ANO2
Location
Chr 125,949,140 (GRCh38)
Highest magnitude
3.5Important
Tested on
23andMe, AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GBadVon Willebrand disease, type 2AImportant · 3.0
  2. A;GMost notableBadvon Willebrand diseaseImportant · 3.5
  3. A;AGoodcommon in clinvarTypical · 0.0

SNPedia records rs61751310 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other ANO2 SNPs

All ANO2 SNPs

Notes

From SNPedia

Notes

rs61751310, also known as c.8317T>C, p.Cys2773Arg, and C2010R, is a SNP in the VWF gene on chromosome 12. The rare rs61751310(C) allele is considered pathogenic for Von Willebrand disease, type 2A, according to ClinVar and the VWFdb.

G;G

see discussion at rs61751310

Source and license

Adapted from rs61751310 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.