rs622342

A SNP in the SLC22A1 gene on chromosome 6. Its most notable genotype is C;C: influences dosage for Parkinson's patients

Gene
SLC22A1
Location
Chr 6160,151,834 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
27%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;ANot ratedNo summary available.Typical · 0.061% of people
  2. C;CMost notableNot ratedinfluences dosage for Parkinson's patientsWorth knowing · 2.07% of people

On SNPedia: (A;A), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 61% C;C 7%
  • European ancestry (Utah)A;A 37% C;C 18%
  • Han Chinese (Beijing)A;A 72% C;C 4%
  • Japanese (Tokyo)A;A 68% C;C 4%
  • Yoruba (Nigeria)A;A 72% C;C 1%
  • African ancestry (Southwest US)A;A 63% C;C 2%
  • Chinese (Denver)A;A 73% C;C 2%
  • Luhya (Kenya)A;A 64% C;C 4%
  • Mexican ancestry (Los Angeles)A;A 43% C;C 18%
  • Maasai (Kenya)A;A 75% C;C 3%
  • TuscanA;A 48% C;C 12%

Conditions, medicines and genes

Other SLC22A1 SNPs

All SLC22A1 SNPs

Notes

From SNPedia

Notes

C;C

Parkinson's disease patients needed higher dosages of levodopa and have worse outcomes

References

Source and license

Adapted from rs622342 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.