rs6311(C;C)
3.6x increased risk of sexual dysfunction when taking SSRI Antidepressants.
- Magnitude
- 3.0Important
- Repute
- Bad
- Frequency
- 31%Average of 11 populations
- On SNPedia
- rs6311(C;C)
- Gene
- HTR2A
Frequency
Share of people with C;C in each HapMap population.
- Maasai (Kenya)47%
- Luhya (Kenya)44%
- Yoruba (Nigeria)40%
- Gujarati Indian38%
- Mexican ancestry (Los Angeles)36%
- African ancestry (Southwest US)32%
- European ancestry (Utah)27%
- Japanese (Tokyo)24%
- Tuscan23%
- Han Chinese (Beijing)22%
- Chinese (Denver)14%
Other genotypes of rs6311
Notes
From SNPedia
Selective Seratonin Reuptake Inhibitors (citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), or sertraline (Zoloft)) cause worse sexual dysfunction (a common side-effect) in people with this SNP. Note that research has shown Saffron is effective at reversing the sexual dysfunction from SSRI anti-depressants.
References
Related
Source and license
Adapted from rs6311(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.