rs664677(C;T)

Lower lung cancer and increased breast cancer risk

Magnitude
2.1Worth knowing
Repute
Not rated
Frequency
42%Average of 11 populations
On SNPedia
rs664677(C;T)
Gene
ATM

Frequency

Share of people with C;T in each HapMap population.

  • Maasai (Kenya)54%
  • European ancestry (Utah)53%
  • Chinese (Denver)50%
  • Han Chinese (Beijing)44%
  • Mexican ancestry (Los Angeles)43%
  • Japanese (Tokyo)41%
  • Luhya (Kenya)39%
  • Gujarati Indian39%
  • Yoruba (Nigeria)35%
  • Tuscan33%
  • African ancestry (Southwest US)26%

Other genotypes of rs664677

  1. C;CMost notableNot ratedLower lung cancer and increased breast cancer riskWorth knowing · 2.118% of people

All about rs664677

Notes

From SNPedia

rs664677 polymorphism was associated with decreased lung cancer risk and increased breast cancer risk (for lung cancer: TC vs. TT: OR = 0.76, 95% CI 0.62-0.92, CC vs. TT: OR = 0.80, 95% CI 0.64-0.99 and for breast cancer: TC vs. TT: OR = 1.42, 95% CI 1.17-1.73, CC vs. TT: OR = 1.51, 95% CI 1.21-1.87). PMID 22203481

References

Source and license

Adapted from rs664677(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.