rs669(C;C)

3.8x or higher increased risk for Alzheimers

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
7%Average of 11 populations
On SNPedia
rs669(G;G)Minus strand
Gene
KLRG1

Frequency

Share of people with C;C in each HapMap population.

  • Mexican ancestry (Los Angeles)14%
  • Yoruba (Nigeria)12%
  • Maasai (Kenya)10%
  • European ancestry (Utah)9%
  • Luhya (Kenya)8%
  • Tuscan8%
  • African ancestry (Southwest US)7%
  • Gujarati Indian3%
  • Han Chinese (Beijing)2%
  • Japanese (Tokyo)<1%
  • Chinese (Denver)<1%

Other genotypes of rs669

  1. T;TGoodnormalTypical · 0.059% of people
  2. C;TNot ratedpossibly increased risk for AlzheimersTypical · 0.034% of people

All about rs669

Source and license

Adapted from rs669(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.