rs671(A;A)

Asian Flusher; increased risk of esophageal cancer; East Asian ancestry; Disulfiram not effective for alcoholism.

Magnitude
4.0Very important
Repute
Bad
Frequency
2%Average of 7 populations
On SNPedia
rs671(A;A)
Gene
ALDH2

Frequency

Share of people with A;A in each HapMap population.

  • Chinese (Denver)6%
  • Japanese (Tokyo)4%
  • Han Chinese (Beijing)3%
  • European ancestry (Utah)0%
  • Yoruba (Nigeria)0%
  • Luhya (Kenya)0%
  • Mexican ancestry (Los Angeles)0%

Other genotypes of rs671

  1. A;GBadAsian Flush; worse hangovers; increased risk of esophageal cancer; East Asian ancestry; Disulfiram probably not effective for alcoholism.Important · 3.515% of people
  2. G;GGoodAlcohol Flush: Normal, doesn't flush. Normal hangovers. Normal risk of Alcoholism. Normal risk of Esophageal Cancer. Disulfiram is effective for alcoholism.Worth knowing · 2.083% of people

All about rs671

Notes

From SNPedia

People with this genotype will experience the asian flush, a redness in the face when drinking alcohol. Unable to break down acetaldehyde, a toxic byproduct of alcohol and cigarette smoke. As a result, you are likely to have greatly increased odds of esophageal cancer, especially if you drink or smoke. It also causes worse hangovers. On the bright side, that makes you much less likely to become an alcoholic. If you become an alcoholic anyway, disulfiram (Antabuse) will not be an effective treatment.

Source and license

Adapted from rs671(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.