rs693

A SNP in the APOB gene on chromosome 2. Its most notable genotype is G;G: normal

Gene
APOB
Location
Chr 221,009,323 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
27%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodnormalTypical · 0.061% of people
  2. A;GNot ratedelevated lipidsTypical · 0.032% of people
  3. A;ABadelevated lipidsTypical · 0.07% of people

SNPedia records rs693 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 61% A;G 32% A;A 7%
  • European ancestry (Utah)G;G 25% A;G 52% A;A 23%
  • Han Chinese (Beijing)G;G 91% A;G 10% A;A 0%
  • Japanese (Tokyo)G;G 89% A;G 12% A;A 0%
  • Yoruba (Nigeria)G;G 65% A;G 31% A;A 4%
  • African ancestry (Southwest US)G;G 58% A;G 33% A;A 9%
  • Chinese (Denver)G;G 85% A;G 12% A;A 3%
  • Gujarati IndianG;G 56% A;G 40% A;A 4%
  • Luhya (Kenya)G;G 76% A;G 22% A;A 2%
  • Mexican ancestry (Los Angeles)G;G 36% A;G 55% A;A 9%
  • Maasai (Kenya)G;G 57% A;G 40% A;A 3%
  • TuscanG;G 31% A;G 49% A;A 20%

Other APOB SNPs

All APOB SNPs

Notes

From SNPedia

Notes

rs693 increases susceptibility to Elevated Apolipoprotein B and LDL-Cholesterol for carriers of the T allele

Source and license

Adapted from rs693 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.