rs718265

A SNP in the DHCR24 gene on chromosome 1. Its most notable genotype is A;A: common in clinvar

Gene
DHCR24
Location
Chr 154,854,229 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
40%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in clinvarTypical · 0.017% of people
  2. G;GNot ratedNo summary available.Typical · 0.037% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 17% G;G 37%
  • European ancestry (Utah)A;A 7% G;G 47%
  • Han Chinese (Beijing)A;A 36% G;G 15%
  • Japanese (Tokyo)A;A 28% G;G 20%
  • Yoruba (Nigeria)A;A 12% G;G 37%
  • African ancestry (Southwest US)A;A 12% G;G 35%
  • Chinese (Denver)A;A 40% G;G 14%
  • Gujarati IndianA;A 5% G;G 71%
  • Luhya (Kenya)A;A 9% G;G 52%
  • Mexican ancestry (Los Angeles)A;A 7% G;G 47%
  • Maasai (Kenya)A;A 14% G;G 43%
  • TuscanA;A 14% G;G 30%

Conditions, medicines and genes

Notes

From SNPedia

Notes

G;G

PMID 17510943 Alzheimer's disease cases that carry rs718265(G;G) had lower levels of Abeta(42)

References

Source and license

Adapted from rs718265 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.