rs72554632

A SNP in the MAOA gene on chromosome X. Its most notable genotype is T;T: possible mental retardation

Gene
MAOA
Location
Chr X43,731,784 (GRCh38)
Highest magnitude
5.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon in clinvarTypical · 0.0
  2. C;TBadCarrier for Brunner's SyndromeVery important · 4.0
  3. T;TMost notableBadpossible mental retardationVery important · 5.0

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other MAOA SNPs

All MAOA SNPs

Notes

From SNPedia

Notes

Brunner syndrome is a recessive X-linked disorder characterized by impulsive aggressiveness and mild mental retardation resulting from MAOA deficiency due to the premature stop codon detected by rs72554632. dbSNP reports rs72554632 (C/T; CAT->TAG; QLN->STOP(AMBER)) as probably pathogenic, NP_000231.1 Gln296X.

Source and license

Adapted from rs72554632 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.