rs727503093

A SNP in the HRAS gene on chromosome 11. Its most notable genotype is C;T: Costello syndrome

Gene
HRAS
Location
Chr 11533,881 (GRCh38)
Highest magnitude
7.0Very important
Tested on
23andMe, AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableBadCostello syndromeVery important · 7.0
  2. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs727503093 on the minus strand: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.175G>A (p.Ala59Thr)

C;T

See links via main rs-page

Source and license

Adapted from rs727503093 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.