rs730880028

A SNP in the TUBA4A gene on chromosome 2. Its most notable genotype is A;A: Likely miscall if from Ancestry data; otherwise, ALS mutation

Gene
TUBA4A
Location
Chr 2219,251,056 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. A;AMost notableBadLikely miscall if from Ancestry data; otherwise, ALS mutationImportant · 3.0

SNPedia records rs730880028 on the minus strand: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

A;A

Seen too often in Ancestry v2 data compared to reported frequency worldwide, so likely to be a miscall in data from Ancestry. If your data is not from Ancestry, let us know.

Source and license

Adapted from rs730880028 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.