rs730882143

A SNP in the MFRP gene on chromosome 11. Its most notable genotype is -;A: Carrier of a posterior microphthalmia mutation

Gene
MFRP
Location
Chr 11119,345,569 (GRCh38)
Highest magnitude
3.0Important
Tested on
Not on consumer chips

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. -;-Goodcommon in clinvarTypical · 0.0
  2. -;AMost notableBadCarrier of a posterior microphthalmia mutationImportant · 3.0

SNPedia records rs730882143 on the minus strand: (-;-), (-;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other MFRP SNPs

All MFRP SNPs

Notes

From SNPedia

Notes

aka c.491_492insT (p.Asn167fs)

-;A

Unaffected in absence of a second MFRP gene mutation; see links and text via main rs-page

Source and license

Adapted from rs730882143 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.