rs74315332
A SNP in the MYOC gene on chromosome 1. Its most notable genotype is G;T: Primary open-angle glaucoma
- Gene
- MYOC
- Location
- Chr 1171,636,000 (GRCh38)
- Highest magnitude
- 4.8Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- G;TMost notableBadPrimary open-angle glaucoma
- G;GGoodcommon in clinvar
SNPedia records rs74315332 on the minus strand: (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other MYOC SNPs
- rs28936694A;CPrimary open-angle glaucomaVery important
- rs74315328A;GPrimary open-angle glaucomaVery important
- rs74315329A;GPrimary open-angle glaucomaVery important
- rs74315330A;GPrimary open-angle glaucomaVery important
- rs74315331A;TPrimary open-angle glaucomaVery important
- rs74315334C;TPrimary open-angle glaucomaVery important
- rs74315335C;TPrimary open-angle glaucomaVery important
- rs74315336C;TPrimary open-angle glaucomaVery important
Notes
From SNPedia
Notes
G;T
Pathogenic in ClinVar; see sidebar on main SNP page.
Source and license
Adapted from rs74315332 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.