rs74315397

A SNP in the MKKS gene on chromosome 20. Its most notable genotype is A;T: Carrier of a Bardet-Biedl syndrome mutation

Gene
MKKS
Location
Chr 2010,412,723 (GRCh38)
Highest magnitude
3.0Important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;TMost notableBadCarrier of a Bardet-Biedl syndrome mutationImportant · 3.0
  2. A;AGoodcommon in clinvarTypical · 0.0

SNPedia records rs74315397 on the minus strand: (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

A;T

Unaffected in absence of a second MKKS gene mutation

Source and license

Adapted from rs74315397 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.