rs75076352
A SNP in the RET gene on chromosome 10. Its most notable genotype is T;T: common in clinvar
- Gene
- RET
- Location
- Chr 1043,114,500 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other RET SNPs
- rs74799832C;TMultiple Endocrine Neoplasia IIAVery important
- rs77316810A;TMultiple Endocrine Neoplasia IIAVery important
- rs77503355A;GMultiple Endocrine Neoplasia IIAVery important
- rs77558292C;TMultiple Endocrine Neoplasia IIAVery important
- rs77709286C;GMultiple Endocrine Neoplasia IIAVery important
- rs78935588C;GMultiple Endocrine Neoplasia IIAVery important
- rs79658334C;GMultiple Endocrine Neoplasia IIAVery important
- rs79781594A;GMultiple Endocrine Neoplasia IIAVery important
Notes
From SNPedia
Show notes, about 180 words
Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains. Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC. Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas. A Cys634Gly substitution of the RET proto-oncogene in a family with recurrence of multiple endocrine neoplasia type 2A and cutaneous lichen amyloidosis. Germ-line mutations in nonsyndromic pheochromocytoma. Cushing's syndrome due to ectopic ACTH secretion by bilateral pheochromocytomas in multiple endocrine neoplasia type 2A. Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains. Haplotype analysis of MEN 2 mutations. Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC. A novel case of multiple endocrine neoplasia type 2A associated with two de novo mutations of the RET protooncogene.
Source and license
Adapted from rs75076352 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.