rs753948675

A SNP in the TTN-AS1 gene on chromosome 2. Its most notable genotype is G;T: Not well determined; but possible cardiac implications

Gene
TTN-AS1
Location
Chr 2178,579,850 (GRCh38)
Highest magnitude
4.1Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;TMost notableBadNot well determined; but possible cardiac implicationsVery important · 4.1
  2. T;TGoodcommon in clinvarTypical · 0.0

On SNPedia: (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.67349-2A>C and also c.59645-2A>C Observed in a sudden cardiac death patient and thought to be associated ; ClinVar has not assigned a pathogenicity to the variant on its own, but does indicate likely pathogenic for congenital muscular dystrophy when in cis with c.42315_42318delGAAA

G;T

see text and links via main rs-page

Source and license

Adapted from rs753948675 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.