rs7561528

A SNP in the LOC105373605 gene on chromosome 2. Its most notable genotype is G;G: common/normal

Gene
LOC105373605
Location
Chr 2127,132,061 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
24%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon/normalTypical · 0.066% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 66%
  • European ancestry (Utah)G;G 42%
  • Han Chinese (Beijing)G;G 79%
  • Japanese (Tokyo)G;G 86%
  • Yoruba (Nigeria)G;G 64%
  • African ancestry (Southwest US)G;G 70%
  • Chinese (Denver)G;G 79%
  • Gujarati IndianG;G 80%
  • Luhya (Kenya)G;G 57%
  • Mexican ancestry (Los Angeles)G;G 64%
  • Maasai (Kenya)G;G 59%
  • TuscanG;G 46%

Conditions, medicines and genes

Notes

From SNPedia

Notes

Alzheimer's disease associated, based on large 2011 study Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

Source and license

Adapted from rs7561528 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.