rs7652331

A SNP in the FYCO1 gene on chromosome 3. Its most notable genotype is C;C: normal risk

Gene
FYCO1
Location
Chr 345,921,260 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
15%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratednormal riskTypical · 0.079% of people
  2. C;TNot ratednormal riskTypical · 0.017% of people
  3. T;TBadsomewhat higher risk for prostate cancerTypical · 0.04% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 79% C;T 17% T;T 4%
  • European ancestry (Utah)C;C 47% C;T 39% T;T 14%
  • Han Chinese (Beijing)C;C 99% C;T <1% T;T 0%
  • Japanese (Tokyo)C;C 100% C;T 0% T;T 0%
  • Yoruba (Nigeria)C;C 97% C;T 3% T;T 0%
  • African ancestry (Southwest US)C;C 83% C;T 12% T;T 5%
  • Chinese (Denver)C;C 99% C;T <1% T;T 0%
  • Gujarati IndianC;C 26% C;T 53% T;T 22%
  • Luhya (Kenya)C;C 91% C;T 9% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 86% C;T 14% T;T 0%
  • Maasai (Kenya)C;C 89% C;T 11% T;T <1%
  • TuscanC;C 56% C;T 41% T;T 3%

Conditions, medicines and genes

Other FYCO1 SNPs

All FYCO1 SNPs

Notes

From SNPedia

Notes

rs7652331 is one of seven SNPs found in a combined study of over 1,000 patients to be associated with increased risk for prostate cancer. The risk allele for this SNP is (T); and while the odds ratio was not specifically reported, the probability of false significance (not permuted though) was given as p=4.4 x 10e-5, using a dominant model of risk.

Source and license

Adapted from rs7652331 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.