rs765628635

A SNP in the TDRD7 gene on chromosome 9. Its most notable genotype is -;G: Carrier of a congenital cataract mutation

Gene
TDRD7
Location
Chr 997,460,451 (GRCh38)
Highest magnitude
3.0Important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;GMost notableBadCarrier of a congenital cataract mutationImportant · 3.0
  2. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (-;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Notes

From SNPedia

Notes

aka c.1129del (p.Ala377Profs) Recessively inherited congenital cataract mutation; see OMIM and ClinVar and associated links

-;G

Unaffected in absence of a second TDRD7 gene mutation

Source and license

Adapted from rs765628635 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.