rs76917243
A SNP in the ALDOB gene on chromosome 9. Its most notable genotype is T;T: hereditary fructose intolerance
- Gene
- ALDOB
- Location
- Chr 9101,427,498 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- G;GGoodcommon in clinvar
- G;TBadCarrier for hereditary fructose intolerance mutation
- T;TMost notableBadhereditary fructose intolerance
On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ALDOB SNPs
- i5008215T;THereditary Fructose IntoleranceVery important
- rs1800546C;GCarrier of a hereditary fructose intolerance (HFI) mutationImportant
- rs77718928A;GUnaffected carrier of hereditary fructose intolerance alleleImportant
- rs78340951C;Gcarrier of hereditary fructose intolerance alleleImportant
- rs118204425-;CTTCarrier of a hereditary fructose intolerance mutationImportant
- rs118204426G;TCarrier of a hereditary fructose intolerance mutationImportant
- rs118204428A;GCarrier of a hereditary fructose intolerance mutationImportant
- rs118204430A;GCarrier of a hereditary fructose intolerance mutationImportant
Notes
From SNPedia
Notes
aka c.524C>A (p.Ala175Asp or A175D; sometimes Ala174Asp in older literature); usually considered the second most common ALDOB gene mutation after the most common one, rs1800546
G;T
Unaffected in absence of a second ALDOB gene mutation
Source and license
Adapted from rs76917243 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.