rs776400380
A SNP in the THSD1 gene on chromosome 13. Its most notable genotype is A;G: Possible higher risk for intracranial aneurysm
- Gene
- THSD1
- Location
- Chr 1352,378,592 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;GMost notableBadPossible higher risk for intracranial aneurysm
- G;GGoodcommon/normal
On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other THSD1 SNPs
- rs141140186C;TPossible higher risk for intracranial aneurysmVery important
- rs201805081C;TPossible higher risk for intracranial aneurysmVery important
- rs371717283A;GPossible higher risk for intracranial aneurysmVery important
- rs780150341A;GPossible higher risk for intracranial aneurysmVery important
- rs9536062A;Gunaffected carrier of a non-immune hydrops fetalis mutationImportant
Notes
From SNPedia
Notes
This SNP represents a rare variant in the THSD1 gene on chromosome 13. The minor allele has been reported (in heterozygotes) in a 2016 study to be potentially strongly associated with intracranial Aneurysm.
A;G
see THSD1 and Intracranial Aneurysm
Source and license
Adapted from rs776400380 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.