rs776746(C;T)

Carrier of 1 nonfunctional CYP3A5 allele; drug metabolism affects

Magnitude
2.0Worth knowing
Repute
Not rated
Frequency
34%Average of 11 populations
On SNPedia
rs776746(A;G)Minus strand
Gene
CYP3A5

Frequency

Share of people with C;T in each HapMap population.

  • African ancestry (Southwest US)54%
  • Maasai (Kenya)51%
  • Japanese (Tokyo)43%
  • Mexican ancestry (Los Angeles)40%
  • Chinese (Denver)39%
  • Han Chinese (Beijing)38%
  • Gujarati Indian38%
  • Yoruba (Nigeria)31%
  • Luhya (Kenya)22%
  • Tuscan11%
  • European ancestry (Utah)7%

Other genotypes of rs776746

  1. T;TGoodreference alleleTypical · 0.021% of people
  2. C;CMost notableBadCYP3A5*3 homozygote; CYP3A5 non-expressorWorth knowing · 2.545% of people

All about rs776746

Source and license

Adapted from rs776746(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.