rs80002943
A SNP in the ITGA2B gene on chromosome 17. Its most notable genotype is A;A: Glanzmann's thromboasthenia
- Gene
- ITGA2B
- Location
- Chr 1744,374,732 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- G;GGoodcommon in clinvar
- A;GBadCarrier of a Glanzmann's thromboasthenia allele
- A;AMost notableBadGlanzmann's thromboasthenia
SNPedia records rs80002943 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other ITGA2B SNPs
- rs76811038G;GGlanzmann's thromboastheniaImportant
- rs80277041G;GGlanzmann's thromboastheniaImportant
- rs137852906A;AGlanzmann's thromboastheniaImportant
- rs137852907T;TGlanzmann's thromboastheniaImportant
- rs137852908T;TGlanzmann's thromboastheniaImportant
- rs137852909T;TGlanzmann's thromboastheniaImportant
- rs137852910T;TGlanzmann's thromboastheniaImportant
- rs137852911G;GGlanzmann's thromboastheniaImportant
Notes
From SNPedia
Notes
Glanzmann's thrombasthenia
A;G
Most likely an unaffected carrier of a Glanzmann's thromboasthenia allele.
A;A
Likely to be at high risk for Glanzmann's thromboasthenia, based on carrying two risk alleles for this recessive condition.
Source and license
Adapted from rs80002943 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.