rs80338909

A SNP in the TEK gene on chromosome 9. Its most notable genotype is A;C: tendency for multiple cutaneous and mucosal venous malformations

Gene
TEK
Location
Chr 927,212,710 (GRCh38)
Highest magnitude
5.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon in clinvarTypical · 0.0
  2. A;CMost notableBadtendency for multiple cutaneous and mucosal venous malformationsVery important · 5.0
  3. A;GBadtendency for multiple cutaneous and mucosal venous malformationsVery important · 5.0

On SNPedia: (A;A), (A;C), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other TEK SNPs

All TEK SNPs

Notes

From SNPedia

Notes

rs80338909, also known as c.2690A>G, p.Tyr897Cys and Y897C, as well as c.2690A>C, Tyr897Ser and Y897S, represents a mutation in the TEK gene on chromosome 9. Both the rare (G) and (C) minor alleles for this SNP are reported to cause Multiple cutaneous and mucosal venous malformations. Allelic and locus heterogeneity in inherited venous malformations.

A;C

see rs80338909

A;G

see rs80338909

Source and license

Adapted from rs80338909 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.