rs80356491

A SNP in the SLC37A4 gene on chromosome 11. Its most notable genotype is -;-: glycogen storage disease type 1b

Gene
SLC37A4
Location
Chr 11119,025,271 (GRCh38)
Highest magnitude
5.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;-Most notableBadglycogen storage disease type 1bVery important · 5.0
  2. -;CTBadcarrier for glycogen storage disease type 1b alleleImportant · 3.0
  3. CT;CTGoodcommon in clinvarTypical · 0.0

On SNPedia: (-;-), (-;CT), (CT;CT). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other SLC37A4 SNPs

All SLC37A4 SNPs

Notes

From SNPedia

Notes

rs80356491, also known as 1042_1043delCT or 1211-1212delCT, is a SNP in the solute carrier family 37 (glucose-6-phosphate transporter), member 4 SLC37A4 gene. This mutation is reported by 23andMe as accounting for approximately 30% of glycogen storage disease type 1b-causing mutations in people of European ancestry; 23andMe uses the term i5012880 for this SNP.

Source and license

Adapted from rs80356491 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.