rs80358192

A SNP in the COL8A2 gene on chromosome 1. Its most notable genotype is A;C: Corneal dystrophy Fuchs endothelial 1

Gene
COL8A2
Location
Chr 136,098,332 (GRCh38)
Highest magnitude
4.0Very important
Tested on
Not on consumer chips

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;CMost notableBadCorneal dystrophy Fuchs endothelial 1Very important · 4.0
  2. A;AGoodcommon in complete genomicsTypical · 0.0

SNPedia records rs80358192 on the minus strand: (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other COL8A2 SNPs

All COL8A2 SNPs

Source and license

Adapted from rs80358192 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.