rs80358250

A SNP in the CFL2 gene on chromosome 14. Its most notable genotype is T;T: Nemaline Myopathy 7

Gene
CFL2
Location
Chr 1434,713,462 (GRCh38)
Highest magnitude
4.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBadNemaline Myopathy 7Very important · 4.0
  2. C;TNot ratedcarrier for Nemaline Myopathy 7Minor · 1.0
  3. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs80358250 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Source and license

Adapted from rs80358250 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.