rs806368(C;C)
Associated with Alcohol Dependence; associated with nicotine dependence (female)
- Magnitude
- 2.5Worth knowing
- Repute
- Bad
- Frequency
- 10%Average of 11 populations
- On SNPedia
- rs806368(C;C)
- Gene
- CNR1
Frequency
Share of people with C;C in each HapMap population.
- Chinese (Denver)29%
- Japanese (Tokyo)28%
- Han Chinese (Beijing)28%
- Mexican ancestry (Los Angeles)10%
- Gujarati Indian5%
- European ancestry (Utah)4%
- Tuscan4%
- Luhya (Kenya)<1%
- Yoruba (Nigeria)<1%
- Maasai (Kenya)<1%
- African ancestry (Southwest US)0%
Other genotypes of rs806368
Notes
From SNPedia
PMID 22085192 Cannabinoid Receptor 1 Gene is Associated with Alcohol Dependence. Alcoholic patients with TGT haplotype (corresponding to rs6454674-rs1049353-rs806368 polymorphisms in this order) were less prone to have AD (p = 0.017). TGC haplotype were more likely to develop AD. PMID 18606954 Cannabinoid receptor 1 gene association with nicotine dependence. the associations were female specific. Haplotype 1-1-2 of markers rs2023239-rs12720071-rs806368(C) was associated with nicotine dependence and FTND score in the 2 samples (P < .001 and P = .009, respectively).
References
Source and license
Adapted from rs806368(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.