rs8176038

A SNP in the KEL gene on chromosome 7. Its most notable genotype is G;G: Kell blood group; Jsa/Jsa (aka Js(a+b-)) antigen

Gene
KEL
Location
Chr 7142,943,026 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
2%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedKell blood group; Jsa/Jsa (aka Js(a+b-)) antigenMinor · 1.00% of people
  2. A;GNot ratedKell blood group; Jsa/Jsb antigen (heterozygote)Minor · 1.09% of people
  3. A;AGoodcommon in clinvar; Kell blood group, Jsb/Jsb antigenTypical · 0.091% of people

SNPedia records rs8176038 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageG;G 0% A;G 9% A;A 91%
  • European ancestry (Utah)G;G 0% A;G 0% A;A 100%
  • Han Chinese (Beijing)G;G 0% A;G 0% A;A 100%
  • Japanese (Tokyo)G;G 0% A;G 0% A;A 100%
  • Yoruba (Nigeria)G;G 0% A;G 21% A;A 79%
  • African ancestry (Southwest US)G;G 0% A;G 16% A;A 84%
  • Luhya (Kenya)G;G 0% A;G 19% A;A 81%
  • Mexican ancestry (Los Angeles)G;G 0% A;G 2% A;A 98%
  • Maasai (Kenya)G;G 0% A;G 14% A;A 86%

Other KEL SNPs

All KEL SNPs

Notes

From SNPedia

Notes

aka c.1790T>C, p.Leu597Pro or L597P encodes the KEL7/KEL6 alleles (and thereby the Jsb/Jsa antigens, respectively) of the KEL blood group

Source and license

Adapted from rs8176038 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.