rs822387

A SNP on chromosome 3. Its most notable genotype is C;C: may have higher adiponectin levels

Gene
None listed
Location
Chr 3186,838,248 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedmay have higher adiponectin levelsMinor · 1.03% of people
  2. C;TNot ratedmay have higher adiponectin levelsMinor · 1.022% of people

On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 3% C;T 22%
  • European ancestry (Utah)C;C 0% C;T 16%
  • Han Chinese (Beijing)C;C 0% C;T 3%
  • Japanese (Tokyo)C;C 0% C;T 22%
  • Yoruba (Nigeria)C;C 12% C;T 48%
  • African ancestry (Southwest US)C;C 4% C;T 46%
  • Chinese (Denver)C;C 0% C;T 6%
  • Gujarati IndianC;C 0% C;T 2%
  • Luhya (Kenya)C;C 8% C;T 42%
  • Mexican ancestry (Los Angeles)C;C 0% C;T 12%
  • Maasai (Kenya)C;C 5% C;T 35%
  • TuscanC;C 2% C;T 12%

Conditions, medicines and genes

Notes

From SNPedia

Notes

A 2008 article showed higher adiponectin levels with rs17300539 (Minor A is risk allele) with strong significance P(n) = 2.6 x 10(-8) and rs822387 (Minor C allele ) with a significance of (P(n) = 3.8 x 10(-5), but neither SNP was associated with diabetes risk. Only minor C allele of rs17366743 had a hazard ratio of "1.94 for incident diabetes (95% CI 1.16–3.25; Pn = 0.01)"

Source and license

Adapted from rs822387 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.