rs841(A;A)

Decreased baroreflex sensitivity, heart rate variability, and in women, hypertension

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
8%Average of 11 populations
On SNPedia
rs841(T;T)Minus strand
Gene
GCH1

Frequency

Share of people with A;A in each HapMap population.

  • Japanese (Tokyo)18%
  • Han Chinese (Beijing)14%
  • Maasai (Kenya)13%
  • Chinese (Denver)12%
  • Mexican ancestry (Los Angeles)7%
  • Yoruba (Nigeria)5%
  • Luhya (Kenya)5%
  • European ancestry (Utah)5%
  • African ancestry (Southwest US)4%
  • Gujarati Indian2%
  • Tuscan2%

Other genotypes of rs841

  1. G;GGoodcommon in clinvarTypical · 0.052% of people

All about rs841

Notes

From SNPedia

In addition to the effects listed in the summary, tight linkage disequilibrium has been observed between this SNP and the "X" GCH1 gene haplotype known as gs224 here in SNPedia.

Source and license

Adapted from rs841(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.