rs851715
A SNP in the CNTNAP2 gene on chromosome 7. Its most notable genotype is T;T: risk of nonsense-word repetition problems if speech-impaired
- Gene
- CNTNAP2
- Location
- Chr 7147,829,814 (GRCh38)
- Highest magnitude
- 1.2Minor
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 25%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TMost notableBadrisk of nonsense-word repetition problems if speech-impaired
- C;TNot ratedNo summary available.
- C;CNot ratedNo summary available.
SNPedia records rs851715 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageT;T 61% C;T 30% C;C 9%
- European ancestry (Utah)T;T 46% C;T 40% C;C 14%
- Han Chinese (Beijing)T;T 31% C;T 47% C;C 22%
- Japanese (Tokyo)T;T 50% C;T 45% C;C 5%
- Yoruba (Nigeria)T;T 100% C;T 0% C;C 0%
- African ancestry (Southwest US)T;T 84% C;T 14% C;C 2%
- Chinese (Denver)T;T 32% C;T 50% C;C 18%
- Gujarati IndianT;T 53% C;T 42% C;C 6%
- Mexican ancestry (Los Angeles)T;T 55% C;T 31% C;C 14%
- Maasai (Kenya)T;T 97% C;T 3% C;C 0%
- TuscanT;T 60% C;T 34% C;C 6%
Related
Conditions, medicines and genes
Other CNTNAP2 SNPs
- rs2710102A;ADelayed childhood speech.Worth knowing
- rs7794745A;Tslightly increased risk for autismWorth knowing
- rs17236239G;Ghigher risk for speech development delay and/or impairmentWorth knowing
- rs759178C;Chigher risk of speech development delay and/or impairmentTypical
- rs802568T;Tcommon in complete genomicsTypical
- rs1358075T;Tcommon genotypeTypical
- rs1718101C;CNo summary available.Typical
- rs2538976T;TNo summary available.Typical
Notes
From SNPedia
Notes
Speech development rs4431523, rs17236239 and significant associations (with P values from 0.01 to 5.0x10–5) between nonsense-word repetition and nine intronic SNPs (rs851715, rs10246256, rs2710102, rs759178, rs1922892, rs2538991, rs17236239, rs2538976, and rs2710117)
Source and license
Adapted from rs851715 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.