rs863224521
A SNP in the PALB2 gene on chromosome 16. Its most notable genotype is A;A: Fanconi anemia, complementation group N
- Gene
- PALB2
- Location
- Chr 1623,629,683 (GRCh38)
- Highest magnitude
- 7.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- -;-Goodcommon/normal
- -;ABadPALB2-related cancer risk
- A;AMost notableBadFanconi anemia, complementation group N
SNPedia records rs863224521 on the minus strand: (-;-), (-;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other PALB2 SNPs
- rs118203997T;TFanconi anemia, complementation group NVery important
- rs118203998C;CFanconi anemia, complementation group NVery important
- rs118203999A;AFanconi anemia, complementation group NVery important
- rs180177083A;AFanconi anemia, complementation group NVery important
- rs180177084-;-Fanconi anemia, complementation group NVery important
- rs180177085-;-Fanconi anemia, complementation group NVery important
- rs180177090-;-Fanconi anemia, complementation group NVery important
- rs180177091A;AFanconi anemia, complementation group NVery important
Notes
From SNPedia
Notes
-;A
]
A;A
see discussion at PALB2
Source and license
Adapted from rs863224521 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.