rs875989816

A SNP in the TGFB3 gene on chromosome 14. Its most notable genotype is A;G: Loeys-Dietz Syndrome

Gene
TGFB3
Location
Chr 1475,965,586 (GRCh38)
Highest magnitude
7.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. A;GMost notableBadLoeys-Dietz SyndromeVery important · 7.0
  2. A;AGoodcommon in clinvarTypical · 0.0

SNPedia records rs875989816 on the minus strand: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other TGFB3 SNPs

All TGFB3 SNPs

Source and license

Adapted from rs875989816 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.