rs876660428

A SNP. Its most notable genotype is G;T: Likely false positive miscall in 23andMe raw data; otherwise, Neurofibromatosis type 1

Gene
None listed
Highest magnitude
5.5Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GGoodcommon/normalTypical · 0.0
  2. G;TMost notableBadLikely false positive miscall in 23andMe raw data; otherwise, Neurofibromatosis type 1Very important · 5.5

On SNPedia: (G;G), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.4243G>T and also c.4243G>A; in ClinVar, the former is considered pathogenic for type 1 neurofibromatosis, while the latter is of uncertain significance 23andMe name for c.4243G>T: i5046667. Note: 23andMe is prone to producing errors (false positives) for the i5046667 mutation.

G;T

see links via main rs-page and also NF1

Source and license

Adapted from rs876660428 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.