rs878854690
A SNP in the CDH1 gene on chromosome 16. Its most notable genotype is -;G: Hereditary diffuse gastric cancer
- Gene
- CDH1
- Location
- Chr 1668,801,866 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Goodcommon in clinvar
- -;GMost notableBadHereditary diffuse gastric cancer
On SNPedia: (-;-), (-;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other CDH1 SNPs
- rs121964873G;TCDH1-based gastric cancer riskVery important
- rs121964874C;TCDH1-based gastric cancer riskVery important
- rs121964876G;TFalse positives possible; otherwise, Hereditary cancer-predisposing syndromeVery important
- rs121964877C;TCDH1-based gastric cancer riskVery important
- rs267606712A;GCDH1-based gastric cancer riskVery important
- rs587776398G;TCDH1-based gastric cancer riskVery important
- rs587780113A;GCDH1-based gastric cancer riskVery important
- rs587780784C;TCDH1-based gastric cancer riskVery important
Notes
From SNPedia
Notes
Also known as c.360dupG, the minor allele is considered a pathogenic rare mutation for hereditary diffuse gastric cancer in ClinVar.
-;G
see CDH1 and rs878854690
Source and license
Adapted from rs878854690 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.