rs9005

A SNP in the IL1RN gene on chromosome 2. Its most notable genotype is G;G: common in complete genomics

Gene
IL1RN
Location
Chr 2113,133,835 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
30%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.049% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageG;G 49%
  • European ancestry (Utah)G;G 39%
  • Han Chinese (Beijing)G;G 45%
  • Japanese (Tokyo)G;G 46%
  • Yoruba (Nigeria)G;G 69%
  • African ancestry (Southwest US)G;G 58%
  • Chinese (Denver)G;G 47%
  • Gujarati IndianG;G 35%
  • Mexican ancestry (Los Angeles)G;G 20%
  • Maasai (Kenya)G;G 81%
  • TuscanG;G 46%

Notes

From SNPedia

Notes

Radiographic severity of knee osteoarthritis is conditional on Interleukin 1 Receptor Antagonist gene variations.

Source and license

Adapted from rs9005 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.