rs924607(T;T)

In childhood acute lymphoblastic leukemia patients, worse response to vincristine

Magnitude
1.5Minor
Repute
Bad
Frequency
9%Average of 11 populations
On SNPedia
rs924607(T;T)
Gene
LOC100996325

Frequency

Share of people with T;T in each HapMap population.

  • Tuscan24%
  • European ancestry (Utah)17%
  • Han Chinese (Beijing)17%
  • Gujarati Indian12%
  • Japanese (Tokyo)11%
  • Mexican ancestry (Los Angeles)9%
  • Chinese (Denver)8%
  • African ancestry (Southwest US)2%
  • Yoruba (Nigeria)<1%
  • Maasai (Kenya)<1%
  • Luhya (Kenya)0%

Other genotypes of rs924607

  1. C;CGoodcommon/normalTypical · 0.058% of people
  2. C;TGoodcommon/normalTypical · 0.033% of people

All about rs924607

Notes

From SNPedia

(T;T) pediatric ALL patients being treated with vincristine have twice the risk of developing peripheral neuropathies compared to (C;C) and (C;T) patients, based on a preliminary study of ~300 patients.

Source and license

Adapted from rs924607(T;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.