rs926103(T;T)

Possible increased risk of multiple sclerosis if SH2D2A promoter GA repeat=16

Magnitude
1.0Minor
Repute
Bad
Frequency
21%Average of 9 populations
On SNPedia
rs926103(A;A)Minus strand
Gene
SH2D2A

Frequency

Share of people with T;T in each HapMap population.

  • Yoruba (Nigeria)57%
  • European ancestry (Utah)48%
  • African ancestry (Southwest US)34%
  • Maasai (Kenya)22%
  • Tuscan14%
  • Mexican ancestry (Los Angeles)9%
  • Chinese (Denver)5%
  • Japanese (Tokyo)5%
  • Han Chinese (Beijing)<1%

Other genotypes of rs926103

  1. C;TGoodNo increased risk.Typical · 0.043% of people
  2. C;CGoodNo increased risk.Typical · 0.036% of people

All about rs926103

Notes

From SNPedia

Possible increased risk of multiple sclerosis if SH2D2A promoter GA repeat=16. See The SH2D2A gene and susceptibility to multiple sclerosis. The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis rs926103 and a GA repeat polymorphism forming a risk haplotype for Multiple sclerosis

Source and license

Adapted from rs926103(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.