rs9332964

A SNP in the SRD5A2 gene on chromosome 2. Its most notable genotype is T;T: micropenis

Gene
SRD5A2
Location
Chr 231,529,325 (GRCh38)
Highest magnitude
4.0Very important
Tested on
23andMe, AncestryDNA
Minor allele frequency
<1%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableBadmicropenisVery important · 4.0
  2. C;TBadcarrier for mutations linked to micropenisWorth knowing · 2.5
  3. C;CGoodnot linked to micropenisTypical · 0.0

SNPedia records rs9332964 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other SRD5A2 SNPs

All SRD5A2 SNPs

Notes

From SNPedia

Notes

rs9332964 is a nonsynonymous change known as R227Q in the SRD5A2 gene. The SRD5A2 gene encodes steroid 5-alpha-reductase, an enzyme which catalyzes the conversion of testosterone in the body. Polymorphisms in SRD5A2 have been implicated in several disorders of male sexual development such as micropenis. The homozygous rs9332964(A;A) genotype has been observed in several Japenese males with micropenis.

Source and license

Adapted from rs9332964 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.