rs948490589
A SNP in the GALNS gene on chromosome 16. Its most notable genotype is C;T: Carrier of an Mucopolysaccharidosis, MPS-IV-A mutation
- Gene
- GALNS
- Location
- Chr 1688,814,506 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon/normal
- C;TMost notableBadCarrier of an Mucopolysaccharidosis, MPS-IV-A mutation
On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other GALNS SNPs
- rs118204435C;GCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204436A;GCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204438A;TCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204439A;GCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204440C;TCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204441C;GCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204442C;TCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
- rs118204443A;CCarrier of an Mucopolysaccharidosis, MPS-IV-A mutationImportant
Notes
From SNPedia
Notes
aka c.947G>A (p.Cys316Tyr)
C;T
Unaffected in absence of a second GALNS gene mutation
Source and license
Adapted from rs948490589 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.