rs966423(C;T)
Possible elevated thyroid cancer risk
- Magnitude
- 2.0Worth knowing
- Repute
- Bad
- Frequency
- 36%Average of 11 populations
- On SNPedia
- rs966423(C;T)
- Gene
- DIRC3
Frequency
Share of people with C;T in each HapMap population.
- European ancestry (Utah)56%
- Japanese (Tokyo)45%
- Tuscan43%
- Mexican ancestry (Los Angeles)40%
- Han Chinese (Beijing)39%
- Gujarati Indian36%
- African ancestry (Southwest US)33%
- Chinese (Denver)29%
- Yoruba (Nigeria)29%
- Maasai (Kenya)25%
- Luhya (Kenya)18%
Other genotypes of rs966423
Notes
From SNPedia
After combining the results, three variants were shown to associate with thyroid cancer: rs966423 on 2q35 (OR = 1.34; P(combined) = 1.3 × 10(-9)), rs2439302 on 8p12 (OR = 1.36; P(combined) = 2.0 × 10(-9)) and rs116909374 on 14q13.3 (OR = 2.09; P(combined) = 4.6 × 10(-11)), a region previously reported to contain an uncorrelated variant conferring risk of thyroid cancer.
Source and license
Adapted from rs966423(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.