rs9888739

A SNP in the ITGAM gene on chromosome 16. Its most notable genotype is C;C.

Gene
ITGAM
Location
Chr 1631,301,932 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
22%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedNo summary available.Typical · 0.062% of people

On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 62%
  • European ancestry (Utah)C;C 82%
  • Han Chinese (Beijing)C;C 98%
  • Japanese (Tokyo)C;C 100%
  • Yoruba (Nigeria)C;C 14%
  • African ancestry (Southwest US)C;C 26%
  • Chinese (Denver)C;C 96%
  • Gujarati IndianC;C 59%
  • Luhya (Kenya)C;C 15%
  • Mexican ancestry (Los Angeles)C;C 85%
  • Maasai (Kenya)C;C 38%
  • TuscanC;C 70%

Conditions, medicines and genes

Other ITGAM SNPs

All ITGAM SNPs

Notes

From SNPedia

Notes

The T allele of rs9888739 is associated with higher risk of systemic lupus erythematosus. NEJM a combined analysis of the 7380 independent samples generated a maximum combined P=2.02x10–26 and an odds ratio of 1.65 for the association between the T allele of rs9888739 and lupus.

Source and license

Adapted from rs9888739 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.