rs991967
A SNP in the TGFB2 gene on chromosome 1. Its most notable genotype is A;A: common in clinvar
- Gene
- TGFB2
- Location
- Chr 1218,442,109 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 48%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageA;A 27%
- European ancestry (Utah)A;A 62%
- Han Chinese (Beijing)A;A 9%
- Japanese (Tokyo)A;A 7%
- Yoruba (Nigeria)A;A 25%
- African ancestry (Southwest US)A;A 32%
- Chinese (Denver)A;A 7%
- Gujarati IndianA;A 40%
- Mexican ancestry (Los Angeles)A;A 27%
- Maasai (Kenya)A;A 16%
- TuscanA;A 44%
Related
Other TGFB2 SNPs
- rs863223797-;CThoracic aortic aneurysm (potential causative mutation)Very important
- rs387907278A;CLoeys-Dietz SyndromeVery important
- rs398122884-;ACAATLoeys-Dietz SyndromeVery important
- rs398122885A;CLoeys-Dietz SyndromeVery important
- rs730880221C;TLoeys-Dietz SyndromeVery important
- rs869025533-;ALoeys-Dietz SyndromeVery important
Source and license
Adapted from rs991967 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.