rs992037
A SNP in the PARK2 gene on chromosome 6. Its most notable genotype is C;C: lowest lysine values
- Gene
- PARK2
- Location
- Chr 6161,580,404 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 28%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CMost notableNot ratedlowest lysine values
- C;TNot ratedintermediate lysine values
- T;TNot ratedhighest lysine values
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageC;C 62% C;T 32% T;T 6%
- European ancestry (Utah)C;C 41% C;T 45% T;T 14%
- Han Chinese (Beijing)C;C 58% C;T 38% T;T 4%
- Japanese (Tokyo)C;C 60% C;T 36% T;T 4%
- Yoruba (Nigeria)C;C 89% C;T 10% T;T <1%
- African ancestry (Southwest US)C;C 74% C;T 23% T;T 4%
- Gujarati IndianC;C 42% C;T 43% T;T 16%
- Luhya (Kenya)C;C 80% C;T 19% T;T <1%
- Maasai (Kenya)C;C 65% C;T 33% T;T 3%
- TuscanC;C 48% C;T 41% T;T 11%
Related
Other PARK2 SNPs
- rs34424986A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853054C;CEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853055A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853056T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853057A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853058T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853059T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853060A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
Notes
From SNPedia
Notes
rs992037 is a SNP located in the Parkinson disease (autosomal recessive, juvenile) 2, parkin PARK2 gene. A study of metabolite concentrations in the blood of 284 adult males from Southern Germany determined that several SNPs were associated either directly with a metabolite range or with a ratio of metabolites. The rarer rs992037(T) allele was associated with increased lysine values. 334px|thumb|left|
Source and license
Adapted from rs992037 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.