rs137853059
A SNP in the PARK2 gene on chromosome 6. Its most notable genotype is T;T: Early-onset (juvenile) Parkinson's disease likely
- Gene
- PARK2
- Location
- Chr 6162,443,314 (GRCh38)
- Highest magnitude
- 9.0Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TMost notableBadEarly-onset (juvenile) Parkinson's disease likely
- A;TBadCarrier of an early-onset Parkinson's mutation
- A;AGoodcommon in clinvar
SNPedia records rs137853059 on the minus strand: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other PARK2 SNPs
- rs34424986A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853054C;CEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853055A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853056T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853057A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853058T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853060A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs397514694A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
Notes
From SNPedia
Notes
c.167T>A (p.Val56Glu) 23andMe calls this i5007833
T;T
See Parkinson's disease and PARK2
A;T
see Parkinson's disease
Source and license
Adapted from rs137853059 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.