rs397514694
A SNP in the PARK2 gene on chromosome 6. Its most notable genotype is A;A: Early-onset (juvenile) Parkinson's disease likely
- Gene
- PARK2
- Location
- Chr 6161,350,205 (GRCh38)
- Highest magnitude
- 9.0Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- A;CBadCarrier of an early-onset Parkinson's mutation
- A;AMost notableBadEarly-onset (juvenile) Parkinson's disease likely
SNPedia records rs397514694 on the minus strand: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other PARK2 SNPs
- rs34424986A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853054C;CEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853055A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853056T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853057A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853058T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853059T;TEarly-onset (juvenile) Parkinson's disease likelyVery important
- rs137853060A;AEarly-onset (juvenile) Parkinson's disease likelyVery important
Notes
From SNPedia
Notes
c.1292G>T (p.Cys431Phe) 23andMe calls this i5047025
A;C
see Parkinson's disease and rs397514694
A;A
See Parkinson's disease and rs397514694
Source and license
Adapted from rs397514694 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.